Epidermal growth factor receptor in non small cell lung cancer: Gene copy number and mutational study
Colomer A, Erill N, Verdú M, Román R, Górriz M, Ibáñez R, Menoyo A, Cordon-Cardo C, Puig X.
BIOPAT, Grup Assistència, HISTOPAT Laboratoris, Barcelona, Spain; and Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States.
Background: Activating mutations of the EGFR gene were identified in tumors from patients with non small cell lung cancer (NSCLC) that responded to therapy with tyrosine kinase inhibitors (TKIs). More recently, survival has been reported to significantly increase amongst patients carrying a […]